PENG Yu
Professor
Head of Department of Pharmacy
Email: pengyu@swjtu.edu.cn
Office: Room 617, 3# Building, Jiuli Campus, Southwest Jiaotong University, Chengdu 610031
BIO
Education
PhD, Lanzhou University, Organic Chemistry (2005)
B.S., Lanzhou University, Organic Chemistry (2000)
Employment
Academic Appointments
Professor, School of Life Science and Engineering, Southwest Jiaotong University,
China (2018-present)
Professor, State Key Laboratory of Applied Organic Chemistry, Lanzhou University,
China (2014-2018)
Associate Professor, State Key Laboratory of Applied Organic Chemistry, Lanzhou University,
China (2009-2014)
Postdoctoral Fellow, University of California, Santa Barbara (advisor: Liming Zhang)
(2008-2009)
Lecturer, State Key Laboratory of Applied Organic Chemistry, Lanzhou University,
China (2005-2009)
Administrative Appointments
Head, Department of Pharmacy (2018-)
Research Interests
Total synthesis, Natural products, Synthetic methodology.
SELECTED PUBLICATIONS
Principal Publications of the Last Five Years
1. Short Total Syntheses of C3a-C7′ Linked Diketopiperazine Alkaloids (+)-Asperazine and
(+)-Pestalazine A Enabled by a Ni-Catalyzed Reductive Coupling of Tertiary Alkyl Chloride.
Luo, Long; Zhai, Xiao-Yong; Wang, Ya-Wen; Peng, Yu*; Gong, Hegui*, Chem.-Eur. J. 2019,
25 989-992.
2. Divergent Asymmetric Syntheses of Podophyllotoxin and Related Family Members via
Stereoselective Reductive Ni-Catalysis. Xiao, Jian; Cong, Xiao-Wei; Yang, Gui-Zhen;
Wang, Ya-Wen; Peng, Yu*, Org. Lett. 2018, 20, 1651-1654. (Highlighted by CBG)
3. Stereoselective Synthesis of a Podophyllum Lignan Core by Intramolecular Reductive
Ni-Catalysis. Xiao, Jian; Cong, Xiao-Wei; Yang, Gui-Zhen; Wang, Ya-Wen; Peng, Yu*,
Chem. Commun. 2018, 54, 2040-2043. (Highlighted by X-MOL)
4. Stereospecific Synthesis of Tetrahydronaphtho[2,3-b]furans Enabled by a
Nickel-Promoted Tandem Reductive Cyclization. Peng, Yu*; Xiao, Jian; Xu, Xiao-Bo; Duan,
Shu-Ming; Ren, Li; Shao, Yong-Liang; Wang, Ya-Wen, Org. Lett. 2016, 18, 5170-5173.
(Highlighted by Prof. Paul Knochel in Synfacts 2016, 12, 1296 and X-MOL)
5. Nickel-Mediated Stereocontrolled Synthesis of Spiroketals via Tandem Cyclization-Coupling
of β-Bromo Ketals and Aryl Iodides. Peng, Yu*; Xu, Xiao-Bo; Xiao, Jian; Wang, Ya-Wen,
Chem. Commun. 2014, 50, 472-474.
6. Ni-Catalyzed Reductive Homocoupling of Unactivated Alkyl Bromides at Room Temperature
and Its Synthetic Application. Peng, Yu*; Luo, Long; Yan, Chang-Song; Zhang, Jian-Jian;
Wang, Ya-Wen, J. Org. Chem. 2013, 78, 10960-10967.
7. Nickel-Mediated Inter- and Intramolecular C-S Coupling of Thiols and Thioacetates with Aryl I
odides at Room Temperature. Xu, Xiao-Bo; Liu, Jian; Zhang, Jian-Jian; Wang, Ya-Wen; Peng, Yu*,
Org. Lett. 2013, 15, 550-553.
8. Nickel-Mediated Inter- and Intramolecular Reductive Cross-Coupling of Unactivated Alkyl
Bromides and Aryl Iodides at Room Temperature. Yan, Chang-Song; Peng, Yu*; Xu, Xiao-Bo;
Wang, Ya-Wen, Chem.-Eur. J. 2012, 18, 6039-6048.
Selected Awards and Honors
Specially Appointed Professorship in Sichuan Province (2018)
Professional Activities
Editorial Board Young Member, Chinese Chemical Letter (2016–present)
RESEARCH
Current Research
Total Synthesis of Natural Products and Medicines
Nickel-mediated Synthetic Methods
Research Group
Dr. Xiao is a member of Prof. Peng group.
TEACHING
Primary Teaching areas
Organic Synthesis
Organic Chemistry
Current Courses
Organic Reactions for Drug Synthesis
Design and Synthesis for Drug
GRADUATE SUPERVISION
I am available for supervision. Over the past five years, I have supervised and graduated 3 PhDs
and 9 MSc.
